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KMID : 0361620190540060509
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Journal of the Korean Orthopaedic Association
2019 Volume.54 No. 6 p.509 ~ p.518
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The Efficacy of Detecting a Sentinel Lymph Node through Positron Emission Tomography/Computed Tomography
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Shin Duk-Seop
Na Ho-Dong
Park Jae-Woo
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Abstract
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Purpose: Lymph node metastasis is a very important prognostic factor for all skin cancers and some sarcomas. A sentinel lymph node (SLN) biopsy is the most useful technique for identifying SLNs. Recently, a new generation of diagnostic tools, such as single photon emission computed tomography/computed tomography (SPECT/CT) and positron emission tomography/CT (PET/CT) enabled the detection of SLNs. This study compared the efficacy of PET/CT for detecting lymph node metastases with a SLN biopsy in a single medical center.
Materials and Methods: From 2008 to 2018, 72 skin cancers of sarcoma patients diagnosed with some lymph node involvement in a whole body PET/CT reading were assessed. Patients suspected of lymph node metastasis were sent to biopsy and those suspected to be reactive lesions were observed. The analysis was performed retrospectively using the medical records, clinical information, PET/CT readings, and pathology results.
Results: The age of patients ranged from 14 to 88 years and the mean follow-up period was 2.4 years. Twenty-two patients were suspected of a lymph node metastasis and confirmed. The sensitivity, specificity, positive predictive value and negative predictive value of PET/CT images in sarcoma and non-sarcoma tumors were increased significantly when the expert’s findings were considered together.
Conclusion: PET/CT is effective in detecting lymph node metastases.
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KEYWORD
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skin neoplasm, sarcoma, sentinel lymph node, positron emission tomography/computed tomography
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